Journal of Research and Advancement in Dentistry
Official publication of Magadh University and Kolhan University, Government of Bihar and Jharkhand, India
Official publication of Magadh University and Kolhan University, Government of Bihar and Jharkhand, India
Year : 2019
Volume : Volume 10
Issue : Issue 4
Address for correspondence :
Dr. Daya Shankar.
DayaShankar@gmail.com
Background: OSMF is a potentially malignant disease of the oral cavity associated with areca nut chewing. The present study compared Hyaluronidase and Placental extract in OSMF cases. Materials & Methods: The present study was conducted on 60 patients of OSMF confirmed clinically and histopathologically. Patients were divided into 2 groups of 30 each. Group I patients were prescribed placental extract (2ml) + dexamethasone (4mg/ml) and group II were prescribed hyaluronidase (1500 IU) + dexamethasone (4mg/ml). The mouth opening was measured with Vernier’s calliper. Results: The mean pre- treatment mouth opening in group I was 25.2 mm and in group II was 26.2 mm. Post treatment mouth opening in group I was 26.2 mm and in group II was 32.8 mm. The difference was significant (P< 0.05). The mean pre- treatment burning sensation in group I was 6.52 and in group II was 6.24 mm. Post treatment burning sensation in group I was 1.82 and in group II was 1.20. The difference was significant (P< 0.05). Conclusion: Authors found that both drugs were found to be equally effective in management of OSMF cases.
Keywords: Placental extract, Hyaluronidase, OSMF.
