Year : 2019

Volume : Volume 10

Issue : Issue 1

Address for correspondence :
Dr. Ajay K. Pillai.
AjayKPillai@gmail.com

Abstract

Background:  Background: Extraction of impacted mandibular third molar causes osseous defect at the distal aspect of the adjacent second molar and the use of platelet rich fibrin (PRF) has shown to be a valid technique for promoting early bone regeneration at the osseous defect. Whether addition of demineralised freeze dried bone graft (DFDBA) to the PRF leads to better amelioration of the osseous bone defect has not been studied. We compared the application of DFDBA plus PRF versus PRF alone in the healing of post-extraction lower third molar osseous defect. Materials and Methods: Patients with impacted mandibular third molars were randomly assigned into two groups: Group I: the extraction socket obliterated with DFDBA plus PRF;and Group II: the extraction socket obliterated with PRF alone. Post operative swelling, mouth opening, probing depth, bone density, and alveolar bone height were compared between the two groups.  Results: A total of 40 patients were included in the study and were randomized into the two groups of 20 patients each. Compared to Group II, the patients in Group I showed significantly more swelling at post-operative day-7.At post-operative 1-month and 6-months, patients in Group I showed lesser probing depth, higher bone density, and higher alveolar bone height compared to patients in Group II. Post-operative swelling at day-1 and mouth opening at day-1 and day-7 were comparable between the two groups.  Conclusion: Our study concludes that DFDBA mixed with PRF was more effective than PRF alone when used for obliteration of osseous defects following removal of impacted third molar. The mixture shows early evidence of new bone formation and better amelioration of osseous defect.

Keywords: Bone density; mandibular platelet-rich fibrin; demineralised freeze dried bone graft.