Journal of Research and Advancement in Dentistry
Official publication of Magadh University and Kolhan University, Government of Bihar and Jharkhand, India
Official publication of Magadh University and Kolhan University, Government of Bihar and Jharkhand, India
Year : 2018
Volume : Volume 9
Issue : Issue 2
Address for correspondence :
Dr. Shweta Raghav.
ShwetaRaghav@gmail.com
Background: The chances of infection by Candida albican increase with decrease in immunity due to various systemic conditions. The present study was conducted to assess the level of candida and IgA in patients wearing orthodontic appliances. Materials & Methods: The present study was conducted on 40 patients of age ranged 8-18 years of both genders who were wearing removable orthodontic appliances. Equal number of age and gender matched subjects were taken as control. Patients wearing removable orthodontic appliances were put in group I and those without it in group II. Oral mucosal scrapings were obtained with wooden spatula from tongue margins and buccal mucosa. For assessment of anti candida IgA in saliva, ELISA method was used. Patients were further subdivided into 2 subgroups, patients who had orthodontic appliances and yeasts in their saliva (A), patients who had orthodontic appliances but no yeasts in their saliva (B), control subjects with yeasts in their saliva (C) and control subjects with no yeasts in their saliva (D). Results: Both group I (Experimental) and group II (Control) had equal number of subjects ie. 40 each. Maximum number of C. albicans species was seen in group I (14) and group II (12) followed by C. Krusei in group I (5) and C. glabrata in 4 cases. C. lusitaniae was observed in 2 in group I and no in group II, C. tropicalis 3 in group I. In group I, candida colonies in group I was 1.14± 1.21 CFU/mL and in group II was 1.23± 1.36 CFU/mL. The difference was non- significant (P> 0.05). The mean IgA level in group A was 0.031 and in group B was 0.014, in group C was 0.042 and in group D was 0.037. The difference was significant (P< 0.05). Conclusion: The levels of anti–C. albicans IgA in saliva did not correlate with the presence of Candida or its adherence to epithelial cells. Orthodontic appliances may favor the adherence of Candida species to epithelial cells.
Keywords: Candida, Orthodontic, Saliva.
