Year : 2020

Volume : Volume 11

Issue : Issue 2s

Address for correspondence :
Dr. Suryakanth Malgikar.
drmalgikarsuryakanth@gmail.com

Abstract

Background:  At present, it is unknown to what extent this combination of DMBM-X and type-I collagen may additionally enhance the clinical outcome of the therapy compared with treatment with DMBM-X alone. Aim of the study was to compare clinically and radiographically the treatment of deep intra-bony defects with a demineralized bone matrix-Xenograft (DMBM-X) alone or DMBM-X in combination with type I collagen membrane as a GTR. Methods: 25 intrabony defects in ten patients were divided into Group A (Test) and Group B (Control). The Group A sites were debrided and grafted with DMBM-X and type-I collagen membrane. The Group B sites were debrided and grafted with DMBM-X alone. Probing depth, Relative attachment level and gingival margin position were recorded at baseline, 3, 6 and 9 months. Standardized radiographs were also documented at these intervals. Results: On completion of 9 months, the mean percentage of probing depth reduction and relative attachment level gain achieved was 67.39 versus 43.32; and 55.63 versus 30.71 in the Group A and Group B sites respectively which was statistically significant (P<0.005*). Gingival recession was seen to be non-significant when compared between the experimental and control sites.  Conclusion: Overall, both therapies led to significant improvements of the investigated parameters. The combination of DMBM-X and type-I collagen membrane as GTR was more effective in terms of improving clinical parameters than DMBM-X alone.

Keywords: Demineralized bone matrix – Xenograft; bone graft material; type-I collagen membrane; Guided tissue regeneration; intrabony defect; periodontal regeneration.