Original Article

Year : 2018

Volume : Volume 9

Issue : Issue 3s

Comparative Evaluation of Alkaline Phosphatase (ALP) Levels in Gingival Crevicular Fluid (GCF) and Alveolar Bone Loss in Smokers and Non-Smokers with Chronic Periodontitis Patients: A Clinico-Biochemical Study

Dr. Hiral Parikh.

Address for correspondence :
Dr. Hiral Parikh.
hiralparikh@gmail.com

Abstract


Background:  Chronic Periodontitis is a periodontal disease caused by dental plaque and is more prevalent and severe in smokers and is characterized by deeper pockets with greater attachment loss. The study was carried out to evaluate and compare the clinical parameters, Alkaline phosphatase levels in GCF and radiographical periodontal bone loss in smoker and non-smoker patients with chronic periodontitis. Materials and Methods: 100 patients were recruited in study with 50 patients in each group (Group I and Group II). Ancillary parameters (Plaque index and Gingival Index) and clinical parameters (Probing depth and clinical attachment levels) were recorded in both the groups. GCF was collected with micropipettes and ALP levels were measured. RVG was taken in all the patients at four selected sites. Statistical analysis was done using independent t- test (p ≤ 0.05). Results: All ancillary parameters and clinical parameters were found to be statistically higher in smokers as compared to non-smokers (p ≤ 0.05). GCF levels of ALP were found to be lower (753.395±49.418) in smokers than in non-smoker group (818.259±51.252).  Conclusion: In this study it was concluded that periodontal destruction is greater in smokers as compared to non- smokers with more alveolar bone loss and decreased alkaline Phosphatase levels in GCF of smokers.

Keywords: Gingival Crevicular fluid, Probing Depth, Alkaline Phosphatase, Smokers.