Year : 2022

Volume : Volume 13

Issue : Issue 3

Address for correspondence :
Dr. Suruchi Sisodia
sisodiasuruchi@gmail.com

Abstract

Context: Effective pain management is important during endodontic therapy. Aims: The aim of our study wasto evaluate the anesthetic efficacy of 4% articaine using intra-ligamentary injection technique with and without premedication in irreversible pulpitis of mandibular 1st molar teeth using visual analog scale (VAS). Settings and Design: Present randomized control trial was conducted on 100 patients within the age
group between 20 and 50 years, divided into four groups as follows group 1A for male, 1B for female where intra-ligamentary anesthesia with 4% articaine was given. Group 2A for male, 2B for female where pre-medication of Ibuprofen 400 mg orally given before intra-ligamentary anesthesia. Materials and Methods: In control group, 0.2 ml of 4% Articaine was deposited into the mesio-buccal, disto-buccal, mesiolingual, and disto-lingual line angle of the mandibular first molar. Test group patients were administered with premedication before injection. Statistical Analysis Used: Clinical data were compared between the groups by Student’s paired t-test. P value was ≥ 0.05 were considered statistically non-significant, and P ≤ 0.05, was considered statistically significant. Mean values between the groups were compared using Chi-square test and proportions between two groups were compared using two sample z-test. Results: Mean preoperative pain VAS score in groups 1 and 2 was statistically non-significant (P > 0.05). At pulp, the mean VAS score in Group 1 and 2 was statistically significant (P < 0.05). The maximum pain score in both the groups was statistically significant (P < 0.05). No significant difference between men and women regarding success rates of two comparison groups. Conclusions: premedication with ibuprofen 400 mg increases the anesthetic efficacy of 4% articaine.

Keywords: Articaine, Ibuprofen, Intra-ligamentary anesthesia, Pre-medication.