Year : 2021

Volume : Volume 12

Issue : Issue 2

Address for correspondence :
Dr. Saurav Kumar
dr.saurav.kumar89@gmail.com

Abstract

Background:  Diabetes mellitus commonly known as diabetes in general terms. It is a disease of uncontrolled blood sugar levels. The classic signs and symptoms of diabetes mellitus include the triad of frequent urination (polyuria), increased thirst (polydipsia), and Increased hunger (polyphagia) along with weakness and fatigue. Diabetes is often related to alteration of gingival basement membrane.  Materials & Methods: The gingival biopsy was obtained from the interdental papilla of a tooth distal to second premolar. It was then fixed in formalin and immediately carried to laboratory. Histological were made of thickness of 5 microns and dyed with hematoxylin and eosin, and PAS. Then it was place under light microscope.  Results: This study clearly shows the increase in incidence of basement membrane alteration. Sixty four percent of the patients showed mild mild changes in the basement membrane. Twenty-five percent showed moderate alterations, while ten percent showed severe alterations in basement membrane.  Conclusion: This research stated that arteriosclerosis is increased in the diabetic patients. Further studies with larger group of patients are required for detailed evaluation.

Keywords: Basement membrane, diabetes mellitus, gingiva.