Case Report

Year : 2021

Volume : Volume 12

Issue : Issue 5

Management of Pemphigus Vulgaris Using Dexamethasone Cyclophosphamide Pulse Therapy: A Case Report

Dr. Kriti Sareen,

Address for correspondence :
Dr. Kriti Sareen,
kriti.sareen12@gmail.com

Abstract


Pemphigus vulgaris (PV) is a life-threatening disease belonging to the pemphigus group of autoimmune intraepidermal bullous diseases of the skin and mucosae. The therapeutic management of PV remains challenging and, in some cases, conventional therapy is not adequate to induce clinical remission. The cornerstone of PV treatment remains systemic corticosteroids. Although very effective, long-term corticosteroid administration is characterized by substantial adverse effects. The introduction of dexamethasone-cyclophosphamide pulse (DCP) therapy for the pemphigus group of disorders has revolutionized the therapy of pemphigus. In this case report, standard DCP therapy has also been given to our patient.

Keywords: Corticosteroids, Dexamethasone, Pemphigus, Treatment.