Year : 2020

Volume : Volume 11

Issue : Issue 2s

Address for correspondence :
Dr. Anupam Deka.
anupamdeka@gmail.com

Abstract

Background:  Periodontitis is an inflammatory disease which manifests clinically as loss of supporting periodontal tissues including periodontal ligament, cementum, and alveolar bone. Periodontal therapy is aimed at achieving complete regeneration of these structures. Numerous procedures have been attempted to achieve periodontal regeneration, including root surface conditioning, bone graft placement, guided tissue regeneration and growth factor application. Stem cells, fascinating area of biology, have been used clinically in periodontal regeneration and also in medicine to treat many incurable diseases. Various human and animal studies have confirmed the presence of stem cells in dental tissues including periodontal ligament. This has opened new avenues aiming towards complete periodontal regeneration using cell-based therapies. The search for new regenerative strategies is a challenging field of periodontal research;, and tissue engineering, using stem cells, has recently been shown as a promising approach. This review provides an overview of various types of stem cells in medicine and dentistry and their potential uses especially pertaining to periodontal regeneration.

Keywords: Adult stem cells, periodontal regeneration, stem cells.