Year : 2019

Volume : Volume 10

Issue : Issue 1

Address for correspondence :
Dr. Saurabh Gandhi.
SaurabhGandhi@gmail.com

Abstract

Background:  The specialty of orthodontics is based on ability to produce controlled tooth movement. In our study we have compared the tooth movement by orthodontic force alone (Group-A) to tooth movement with orthodontic force along with Prostaglandin E2 (Group-B) and tooth movement by orthodontic force along with Vitamin D3 (Group-C). A sample of fifteen young male Albino rats of 6 weeks of age and weight of around 160 +10 gms were selected. These samples were divided in three groups containing five rats in each group.  Results of our study depicted that Group B and Group C showed increase in the amount of tooth movement when compared to control group. Mean tooth movement showed by Group A is 1.69 + 0.01mm, Group B is 2.27 + 0.01mm, and for Group C is 2.18 + 0.02mm. This difference was statistically not significant. With Prostaglandin E2 group there is 34.31% more tooth movement compared to control group, and with Vitamin D3 group there is 28.99% more tooth movement compared to control group. Orthodontic tooth movement was enhanced by local injections of both Prostaglandin E2 and Vitamin D3. The osteoclastic activity in the Prostaglandin E2 group was greater than Vitamin D3 group.  The osteoblastic activity in the Vitamin D3 group was greater than the Prostaglandin E2 group favoring better coupling of formation and resorption of alveolar bone remodeling.

Keywords: Orthodontics, Vitamin D3, Tooth movement, Prostaglandin E2.